BDBM50329227 (4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(3-fluorophenyl)-3-(1-(methylsulfonyl)piperidin-4-yl)propyl)hexa hydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone::(4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(3-fluorophenyl)-3-(1-(methylsulfonyl)piperidin-4-yl)propyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone::CHEMBL1269885

SMILES Cc1ncnc(C)c1C(=O)N1C[C@@H]2CN(CCC(C3CCN(CC3)S(C)(=O)=O)c3cccc(F)c3)C[C@@H]2C1

InChI Key InChIKey=PEJVCEUAQSWXGP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329227   

TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329227((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(3-flu...)
Affinity DataIC50: 44nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329227((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(3-flu...)
Affinity DataIC50: 44nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329227((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(3-flu...)
Affinity DataIC50: 500nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329227((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(3-flu...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed