BDBM50329232 ((3aR,6aS)-5-(3-(1-(2,2-difluoroethyl)piperidin-4-yl)-3-(3,5-difluorophenyl)propyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(4,6-dimethylpyrimidin-5-yl)methanone::CHEMBL1270798

SMILES Cc1ncnc(C)c1C(=O)N1C[C@@H]2CN(CCC(C3CCN(CC(F)F)CC3)c3cc(F)cc(F)c3)C[C@@H]2C1

InChI Key InChIKey=HIEMJINKLJLCCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329232   

TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329232(((3aR,6aS)-5-(3-(1-(2,2-difluoroethyl)piperidin-4-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329232(((3aR,6aS)-5-(3-(1-(2,2-difluoroethyl)piperidin-4-...)
Affinity DataIC50: 25nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed