BDBM50329234 (4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(1-(isopropylsulfonyl)piperidin-4-yl)-3-phenylpropyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone::CHEMBL1271000

SMILES CC(C)S(=O)(=O)N1CCC(CC1)C(CCN1C[C@H]2CN(C[C@H]2C1)C(=O)c1c(C)ncnc1C)c1ccccc1

InChI Key InChIKey=YWUQJCUUNVCNFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329234   

TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329234((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(1-(is...)
Affinity DataIC50: 47nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329234((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-(3-(1-(is...)
Affinity DataIC50: 99nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed