BDBM50329256 4,6-dimethyl-5-((3aR,6aS)-5-(3-(1-(methylsulfonyl)piperidin-4-yl)-3-phenylpropyl)octahydropyrrolo[3,4-c]pyrrole-2-carbonyl)picolinonitrile::CHEMBL1271208

SMILES Cc1cc(nc(C)c1C(=O)N1C[C@@H]2CN(CCC(C3CCN(CC3)S(C)(=O)=O)c3ccccc3)C[C@@H]2C1)C#N

InChI Key InChIKey=RUGPFTCINDXZAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329256   

TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329256(4,6-dimethyl-5-((3aR,6aS)-5-(3-(1-(methylsulfonyl)...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329256(4,6-dimethyl-5-((3aR,6aS)-5-(3-(1-(methylsulfonyl)...)
Affinity DataIC50: 31nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed