BDBM50329293 (R)-3-Benzyloxycarbonylamino-pyrrolidine-1-carboxylic acid adamantan-2-yl ester::CHEMBL1270409

SMILES O=C(N[C@@H]1CCN(C1)C(=O)OC1C2CC3CC(C2)CC1C3)OCc1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329293   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329293((R)-3-Benzyloxycarbonylamino-pyrrolidine-1-carboxy...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant 11betaHSD1 expressed in CHO cells assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329293((R)-3-Benzyloxycarbonylamino-pyrrolidine-1-carboxy...)
Affinity DataIC50: 84.8nMAssay Description:Inhibition of 11betaHSD1 in human platelet assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed