BDBM50329295 (R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid adamantan-2-yl ester::CHEMBL1270503

SMILES CN(C(=O)OC(C)(C)C)[C@@H]1CCN(C(=O)OC2C3CC4CC(C3)CC2C4)C1

InChI Key InChIKey=LDWNGJZCOABBTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329295   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329295BDBM50329295((R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidi...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant 11betaHSD1 expressed in CHO cells assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329295BDBM50329295((R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidi...)
Affinity DataIC50: 24.7nMAssay Description:Inhibition of 11betaHSD1 in human platelet assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed