BDBM50329295 (R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid adamantan-2-yl ester::CHEMBL1270503

SMILES CN([C@@H]1CCN(C1)C(=O)OC1C2CC3CC(C2)CC1C3)C(=O)OC(C)(C)C

InChI Key InChIKey=LDWNGJZCOABBTF-SVXFNXITSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329295   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329295((R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidi...)
Affinity DataIC50:  24.7nMAssay Description:Inhibition of 11betaHSD1 in human platelet assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329295((R)-3-(tert-Butoxycarbonyl-methyl-amino)-pyrrolidi...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant 11betaHSD1 expressed in CHO cells assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed