BDBM50329464 5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-2-yl)-1Hpyrrole-3-carboxamide::CHEMBL1270618::US9670191, G14

SMILES Cn1c(-c2[nH]c(-c3ccnc(N)n3)cc2C(N)=O)cc2ccccc21

InChI Key InChIKey=IYFKRIWGRGFLBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329464   

TargetCell division cycle 7-related protein kinase(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329464BDBM50329464(5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50329464BDBM50329464(5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent