BDBM50329658 CHEMBL1271047::ethyl 5-isopropoxy-4-methyl-9H-pyrido[3,4-b]indole-3-carboxylate

SMILES CCOC(=O)c1ncc2[nH]c3cccc(OC(C)C)c3c2c1C

InChI Key InChIKey=VMDUABMKBUKKPG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329658   

TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329658(ethyl 5-isopropoxy-4-methyl-9H-pyrido[3,4-b]indole...)
Affinity DataKi:  137nMAssay Description:Agonist activity at human recombinant GABAA alpha-3-beta-3-gamma-2 receptor expressed in Xenopus oocytes at 1 to 10 uM by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329658(ethyl 5-isopropoxy-4-methyl-9H-pyrido[3,4-b]indole...)
Affinity DataKi:  137nMAssay Description:Agonist activity at human recombinant GABAA alpha-4-beta-3-gamma-2 receptor expressed in Xenopus oocytes at 1 to 10 uM by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329658(ethyl 5-isopropoxy-4-methyl-9H-pyrido[3,4-b]indole...)
Affinity DataKi:  137nMAssay Description:Agonist activity at human recombinant GABAA alpha-1-beta-3-gamma-2 receptor expressed in Xenopus oocytes at 1 to 10 uM by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50329658(ethyl 5-isopropoxy-4-methyl-9H-pyrido[3,4-b]indole...)
Affinity DataKi:  137nMAssay Description:Agonist activity at human recombinant GABAA alpha-2-beta-3-gamma-2 receptor expressed in Xenopus oocytes at 1 to 10 uM by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed