BDBM50330509 5-(4-Methylpiperazin-1-yl)-3-(thiophen-2-ylsulfonyl)-1H-indazole::CHEMBL1277010

SMILES CN1CCN(CC1)c1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccs1

InChI Key InChIKey=DALKVJHTYVRNFB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330509   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330509(5-(4-Methylpiperazin-1-yl)-3-(thiophen-2-ylsulfony...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50330509(5-(4-Methylpiperazin-1-yl)-3-(thiophen-2-ylsulfony...)
Affinity DataIC50:  331nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells by cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed