BDBM50330750 CHEMBL1277126

SMILES OC(=O)C1=CCN(CC1)C1CCC2(C1)Cc1ccccc1Oc1ccccc21

InChI Key InChIKey=NYWUAMYWDNANQG-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50330750   

TargetHistamine H1 receptor(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in Sprague-Dawley rat cortical membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataKi:  50.1nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6 transfected in bactosome expression system by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9 transfected in bactosome expression system by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 transfected in bactosome expression system by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 transfected in bactosome expression system by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50330750(CHEMBL1277126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19 transfected in bactosome expression system by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed