BDBM50330947 CHEMBL1277792::N-((3-Morpholinopyridin-4-yl)methyl)-6-(4-chlorophenyl)-pyrazine-2-carboxamide

SMILES Clc1ccc(cc1)-c1cncc(n1)C(=O)NCc1ccncc1N1CCOCC1

InChI Key InChIKey=XODADHNSUQUULV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330947   

TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330947(N-((3-Morpholinopyridin-4-yl)methyl)-6-(4-chloroph...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330947(N-((3-Morpholinopyridin-4-yl)methyl)-6-(4-chloroph...)
Affinity DataIC50: 4.14E+3nMAssay Description:Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed