BDBM50331568 CHEMBL1289193::N-(4-(1H-pyrazol-3-ylamino)-3,4-dioxobutan-2-yl)-2-chloro-3-(trifluoromethyl)benzamide

SMILES CC(NC(=O)c1cccc(c1Cl)C(F)(F)F)C(=O)C(=O)Nc1ccn[nH]1

InChI Key InChIKey=IGBRTMNMZLDZHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331568   

TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331568(CHEMBL1289193 | N-(4-(1H-pyrazol-3-ylamino)-3,4-di...)
Affinity DataIC50:  51.3nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331568(CHEMBL1289193 | N-(4-(1H-pyrazol-3-ylamino)-3,4-di...)
Affinity DataIC50:  14.1nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed