BDBM50332235 (R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro-5-fluorobenzyl)-1-(3-hydroxypropyl)-3-methyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione hydrochloride::CHEMBL1287844

SMILES Cn1c(=O)n(CCCO)c2cc(N3CCC[C@@](C)(N)C3)n(Cc3cc(F)ccc3Cl)c2c1=O

InChI Key InChIKey=XBMITRBRBFZWMY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50332235   

TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50332235((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50332235((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro...)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50332235((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50332235((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50332235((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50332235((R)-6-(3-amino-3-methylpiperidin-1-yl)-5-(2-chloro...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed