BDBM50333017 3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine::CHEMBL1631902

SMILES c1cnc2[nH]nc(C#Cc3ccncc3)c2c1

InChI Key InChIKey=JGQJFQCPRFMJSP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333017   

LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
LigandPNGBDBM50333017(3-(Pyridin-4-ylethynyl)-1H-pyrazolo[3,4-b]pyridine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed