BDBM50333024 3-((1H-Indazol-3-yl)ethynyl)aniline::CHEMBL1631895
SMILES Nc1cccc(c1)C#Cc1n[nH]c2ccccc12
InChI Key InChIKey=KWDWCNUKZHIQCN-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50333024
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 5.12E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair