BDBM50333217 4-methyl-2-morpholinothiazole-5-carboxylic acid::CHEMBL1645102

SMILES Cc1nc(sc1C(O)=O)N1CCOCC1

InChI Key InChIKey=IGJJRJBRRJIZBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333217   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50333217(4-methyl-2-morpholinothiazole-5-carboxylic acid | ...)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of human p110alpha PI3K fragment by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50333217(4-methyl-2-morpholinothiazole-5-carboxylic acid | ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human PI3K p110delta catalytic subunit by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50333217(4-methyl-2-morpholinothiazole-5-carboxylic acid | ...)
Affinity DataIC50: >8.33E+4nMAssay Description:Inhibition of human PI3K p110gamma catalytic subunit by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50333217(4-methyl-2-morpholinothiazole-5-carboxylic acid | ...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human PI3K p110beta catalytic subunit by AlphaScreen competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed