BDBM50333387 (S)-N-(1-methyl-1H-indazol-5-yl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL1645463

SMILES Cn1ncc2cc(Nc3ncnn4ccc(COC[C@@H]5CNCCO5)c34)ccc12

InChI Key InChIKey=VPNBNXNQPSWMMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333387   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50333387((S)-N-(1-methyl-1H-indazol-5-yl)-5-((morpholin-2-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50333387((S)-N-(1-methyl-1H-indazol-5-yl)-5-((morpholin-2-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed