BDBM50333423 7-(Pyridin-3-ylmethoxy)-1-methyl-beta-carboline::CHEMBL1645552::US9168247, JR212

SMILES Cc1nccc2c3ccc(OCc4cccnc4)cc3[nH]c12

InChI Key InChIKey=DBVRCFMRLBRLQE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333423   

TargetAmine oxidase [flavin-containing] A(Human)
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL
LigandPNGBDBM50333423(7-(Pyridin-3-ylmethoxy)-1-methyl-beta-carboline | ...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Facultes Universitaires Notre Dame De La Paix

US Patent
LigandPNGBDBM50333423(7-(Pyridin-3-ylmethoxy)-1-methyl-beta-carboline | ...)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:A radiometric protein kinase assay (33PanQinase Activity Assay) was used for measuring the kinase activity of DYRK1A protein kinase. All kinase assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Facultes Universitaires Notre Dame De La Paix

US Patent
LigandPNGBDBM50333423(7-(Pyridin-3-ylmethoxy)-1-methyl-beta-carboline | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK1A kinase using RBER-CHKtide substrate by radiometric protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed