BDBM50333446 3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine::CHEMBL1645613

SMILES Fc1cccc(Oc2ccccc2Cl)c1OC1CCNC1

InChI Key InChIKey=UNWRSVCWVWOSPV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333446   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333446(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333446(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine...)
Affinity DataKi:  192nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333446(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine...)
Affinity DataKi:  2.03E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333446(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine...)
Affinity DataKi:  2.23E+3nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed