BDBM50333452 3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)pyridine::CHEMBL1645619

SMILES Fc1cccc(Cl)c1Oc1ncccc1OC1CNC1

InChI Key InChIKey=KCIORJWXNLIEPL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333452   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333452(3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)p...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
LigandPNGBDBM50333452(3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)p...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333452(3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)p...)
Affinity DataKi: >4.26E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333452(3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)p...)
Affinity DataKi: >6.28E+3nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed