BDBM50333468 1-(5-tert-butyl-3-((2-(dimethylamino)ethyl)carbamoyl)thiophen-2-yl)-3-(1H-indazol-5-yl)urea::CHEMBL1641790

SMILES CN(C)CCNC(=O)c1cc(sc1NC(=O)Nc1ccc2[nH]ncc2c1)C(C)(C)C

InChI Key InChIKey=QUNYYWCMQDEBCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333468   

TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333468(1-(5-tert-butyl-3-((2-(dimethylamino)ethyl)carbamo...)
Affinity DataIC50: 521nMAssay Description:Inhibition of S6K1 in ribosomal protein S6 by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333468(1-(5-tert-butyl-3-((2-(dimethylamino)ethyl)carbamo...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of S6K1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed