BDBM50333597 4-(Benzyloxy)-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-pyridin-2(1H)-one::CHEMBL1641614

SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc(OCCN2CCCC2)cc1

InChI Key InChIKey=BZNSXKFFBJLSJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333597   

TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333597(4-(Benzyloxy)-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phen...)
Affinity DataIC50: 5.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333597(4-(Benzyloxy)-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phen...)
Affinity DataIC50: 8.10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]methanes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50333597(4-(Benzyloxy)-1-{4-[2-(pyrrolidin-1-yl)ethoxy]phen...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed