BDBM50334603 2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)pyrimidin-2-ylamino)-8-methoxy-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-N-methylacetamide::CHEMBL1642262

SMILES CNC(=O)CN1CCc2cc(Nc3ncc(Cl)c(Nc4ccc(cc4OC)N4CCOCC4)n3)c(OC)cc2CC1

InChI Key InChIKey=JHDOOEWAYCGNBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334603   

TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334603(2-(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamin...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed