BDBM50335546 7-ethyl-4-methyl-N-(4,4,6-trimethyl-4,5-dihydropyrimidin-2-yl)quinazolin-2-amine::CHEMBL1652422

SMILES CCc1ccc2c(C)nc(NC3=NC(C)(C)CC(C)=N3)nc2c1

InChI Key InChIKey=NGFXXIKLZLDQGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335546   

TargetTrypanothione reductase(Trypanosoma cruzi)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50335546(7-ethyl-4-methyl-N-(4,4,6-trimethyl-4,5-dihydropyr...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi X10/1 trypanothione reductase assessed as inhibition of thionitrobenzoate formation by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed