BDBM50335548 5,6-dimethyl-2-(4,6,8-trimethylquinazolin-2-ylamino)pyrimidin-4-ol::CHEMBL1652424

SMILES Cc1cc(C)c2nc(Nc3nc(C)c(C)c(=O)[nH]3)nc(C)c2c1

InChI Key InChIKey=ZQNLHQMVYUYLMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335548   

TargetTrypanothione reductase(Trypanosoma cruzi)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50335548(5,6-dimethyl-2-(4,6,8-trimethylquinazolin-2-ylamin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi X10/1 trypanothione reductase assessed as inhibition of thionitrobenzoate formation by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed