BDBM50335819 1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol::CHEMBL1650654

SMILES Nc1cccc(c1)-c1c(O)ccc2cc(ccc12)-c1cccc(O)c1

InChI Key InChIKey=DMEBSJDKEXDYPF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50335819   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  53nMAssay Description:Displacement of [3H]E1 from human placental 17beta-HSD1 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  1.76E+3nMAssay Description:Displacement of [3H]E2 from human placental 17beta-HSD2 after 10 mins by fluid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50335819(1-(3-Aminophenyl)-6-(3-hydroxyphenyl)-2-naphthol |...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed