BDBM50336001 CHEMBL1669020::N-(4-(5,9-diethoxy-6-oxo-6H-pyrrolo[3,4-g]quinolin-7(8H)-yl)-3-methylphenethyl)-2-(2-methoxyphenyl)acetamide

SMILES CCOc1c2C(=O)N(Cc2c(OCC)c2ncccc12)c1ccc(CCNC(=O)Cc2ccccc2OC)cc1C

InChI Key InChIKey=ZWBDUXHGKGRKRI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336001   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50336001(N-(4-(5,9-diethoxy-6-oxo-6H-pyrrolo[3,4-g]quinolin...)
Affinity DataKi:  0.870nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as PGE2-induced cAMP accumulation by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50336001(N-(4-(5,9-diethoxy-6-oxo-6H-pyrrolo[3,4-g]quinolin...)
Affinity DataKi:  2.60nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as PGE2-induced cAMP accumulation by scintillation proximity assay in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed