BDBM50336722 2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzamide::CHEMBL1671916

SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)Nc1nccs1

InChI Key InChIKey=HYWCKSHSBGMFFR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50336722   

TargetAdenosine receptor A2a(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in high five cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant CYP2C19 after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2D6 after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2 after 28 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50336722(2-methyl-N-(4-(thiazol-2-ylcarbamoyl)phenyl)benzam...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C9 after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed