BDBM50336932 CHEMBL1672546::N-(3-(4-cyano-3-methoxyphenyl)-1-isopropyl-1H-indol-6-yl)methanesulfonamide

SMILES COc1cc(ccc1C#N)-c1cn(C(C)C)c2cc(NS(C)(=O)=O)ccc12

InChI Key InChIKey=CUIMAZBZRVOSOP-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50336932   

TargetProgesterone receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336932(CHEMBL1672546 | N-(3-(4-cyano-3-methoxyphenyl)-1-i...)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336932(CHEMBL1672546 | N-(3-(4-cyano-3-methoxyphenyl)-1-i...)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]methyltrienolone from human androgen receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336932(CHEMBL1672546 | N-(3-(4-cyano-3-methoxyphenyl)-1-i...)
Affinity DataKi:  977nMAssay Description:Displacement of [3H]methyltrienolone from human glucocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336932(CHEMBL1672546 | N-(3-(4-cyano-3-methoxyphenyl)-1-i...)
Affinity DataKi:  1.39E+3nMAssay Description:Displacement of [3H]methyltrienolone from human mineralocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336932(CHEMBL1672546 | N-(3-(4-cyano-3-methoxyphenyl)-1-i...)
Affinity DataIC50:  2.42E+3nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336932(CHEMBL1672546 | N-(3-(4-cyano-3-methoxyphenyl)-1-i...)
Affinity DataIC50:  7.28nMAssay Description:Antagonist activity at human progesterone receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by GRE-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed