BDBM50336934 CHEMBL1672545::N-(3-(4-cyanophenyl)-1-isopropyl-1H-indol-6-yl)methanesulfonamide

SMILES CC(C)n1cc(-c2ccc(cc2)C#N)c2ccc(NS(C)(=O)=O)cc12

InChI Key InChIKey=LGAUBOVPGJHLSD-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50336934   

TargetProgesterone receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336934(CHEMBL1672545 | N-(3-(4-cyanophenyl)-1-isopropyl-1...)
Affinity DataKi:  0.795nMAssay Description:Displacement of [3H]methyltrienolone from human progesterone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336934(CHEMBL1672545 | N-(3-(4-cyanophenyl)-1-isopropyl-1...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]methyltrienolone from human mineralocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336934(CHEMBL1672545 | N-(3-(4-cyanophenyl)-1-isopropyl-1...)
Affinity DataKi:  1.53E+3nMAssay Description:Displacement of [3H]methyltrienolone from human glucocorticoid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336934(CHEMBL1672545 | N-(3-(4-cyanophenyl)-1-isopropyl-1...)
Affinity DataKi: >3.90E+3nMAssay Description:Displacement of [3H]methyltrienolone from human androgen receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336934(CHEMBL1672545 | N-(3-(4-cyanophenyl)-1-isopropyl-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336934(CHEMBL1672545 | N-(3-(4-cyanophenyl)-1-isopropyl-1...)
Affinity DataIC50:  6.81nMAssay Description:Antagonist activity at human progesterone receptor expressed in HEK293 cells assessed as inhibition of R5050-induced transcriptional activity by GRE-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed