BDBM50336967 CHEMBL1672579::ethyl 5-(4-iodophenyl)-1-(4-sulfamoylphenyl)-1H-pyrazole-3-carboxylate

SMILES CCOC(=O)c1cc(-c2ccc(I)cc2)n(n1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=KWODIPMMQSPOJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336967   

TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50336967(ethyl 5-(4-iodophenyl)-1-(4-sulfamoylphenyl)-1H-py...)
Affinity DataIC50: 260nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50336967(ethyl 5-(4-iodophenyl)-1-(4-sulfamoylphenyl)-1H-py...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of COX2 in mouse LPS-stimulated RAW264.7 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50336967(ethyl 5-(4-iodophenyl)-1-(4-sulfamoylphenyl)-1H-py...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed