BDBM50337499 6-(phenylethynyl)-3,4-dihydronaphthalen-1(2H)-one::CHEMBL1682795

SMILES O=C1CCCc2cc(ccc12)C#Cc1ccccc1

InChI Key InChIKey=LKAKPGPUSCLZCZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337499   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337499(6-(phenylethynyl)-3,4-dihydronaphthalen-1(2H)-one ...)
Affinity DataEC50:  589nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed