BDBM50337504 6-(phenylethynyl)isoquinolin-1(2H)-one::CHEMBL1682800

SMILES O=c1[nH]ccc2cc(ccc12)C#Cc1ccccc1

InChI Key InChIKey=KPQINVQRCIJTEX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337504   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337504(6-(phenylethynyl)isoquinolin-1(2H)-one | CHEMBL168...)
Affinity DataEC50:  182nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed