BDBM50337505 CHEMBL1682801::N,N-dimethyl-5-(phenylethynyl)pyrimidin-2-amine

SMILES CN(C)c1ncc(cn1)C#Cc1ccccc1

InChI Key InChIKey=YTDMQNNCSBQOAF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337505   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337505(N,N-dimethyl-5-(phenylethynyl)pyrimidin-2-amine | ...)
Affinity DataEC50:  113nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed