BDBM50337507 CHEMBL1682803::N,N-dimethyl-6-(phenylethynyl)pyridazin-3-amine

SMILES CN(C)c1ccc(nn1)C#Cc1ccccc1

InChI Key InChIKey=QWLJKVDIAITQQX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337507   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337507(N,N-dimethyl-6-(phenylethynyl)pyridazin-3-amine | ...)
Affinity DataEC50:  401nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed