BDBM50337508 5-(phenylethynyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine::CHEMBL1682804

SMILES C1Cc2cc(cnc2N1)C#Cc1ccccc1

InChI Key InChIKey=XKYNWQQXPNSPBP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337508   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337508(5-(phenylethynyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyr...)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed