BDBM50337509 1-methyl-5-(phenylethynyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine::CHEMBL1682805

SMILES CN1CCc2cc(cnc12)C#Cc1ccccc1

InChI Key InChIKey=RTSSGJFEKPAXIB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337509   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337509(1-methyl-5-(phenylethynyl)-2,3-dihydro-1H-pyrrolo[...)
Affinity DataEC50:  107nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed