BDBM50337876 (R)-1-(3-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)propyl)piperidin-4-yl biphenyl-2-ylcarbamate::CHEMBL1683931

SMILES O[C@@H](CNCCCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=SMJZXEGGFGRWAA-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50337876   

TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50337876((R)-1-(3-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50337876((R)-1-(3-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-dihydroalprenolol from human beta2-adrenoceptor expressed in HEK cells after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50337876((R)-1-(3-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-N-methyl-scopolamine from human muscarinic M3 receptor after 6 hrs by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed