BDBM50337882 2-((3S)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino)nonyl)pyrrolidin-3-yl)-2,2-diphenylacetamide::CHEMBL1683939

SMILES NC(=O)C([C@@H]1CCN(CCCCCCCCCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)C1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=SKQQIRNICDPYHD-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50337882   

TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50337882(2-((3S)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dih...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50337882(2-((3S)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dih...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-N-methyl-scopolamine from human muscarinic M3 receptor after 6 hrs by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50337882(2-((3S)-1-(9-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dih...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-dihydroalprenolol from human beta2-adrenoceptor expressed in HEK cells after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed