BDBM50337934 (R)-3-(2,3-dihydroxypropoxy)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione::CHEMBL1684075::US8470837, 28

SMILES Cn1c2ncn(OC[C@H](O)CO)c(=O)c2c(Nc2ccc(I)cc2F)c(F)c1=O

InChI Key InChIKey=LZLLSKDGTBHIML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337934   

LigandPNGBDBM50337934(US8470837, 28 | CHEMBL1684075 | (R)-3-(2,3-dihydro...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50337934(US8470837, 28 | CHEMBL1684075 | (R)-3-(2,3-dihydro...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent