BDBM50337942 6-((2,4-difluorophenyl)ethynyl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL1684119

SMILES Fc1ccc(C#Cc2ccc3C(=O)NCCc3c2)c(F)c1

InChI Key InChIKey=CRMBUIXNAOQITN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337942   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337942(6-((2,4-difluorophenyl)ethynyl)-3,4-dihydroisoquin...)
Affinity DataEC50:  850nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed