BDBM50337943 2-((3-fluorophenyl)ethynyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one::CHEMBL1684120

SMILES Fc1cccc(c1)C#Cc1ccc2C(=O)NCCc2n1

InChI Key InChIKey=CCBMCVHJBDQDRF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337943   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337943(2-((3-fluorophenyl)ethynyl)-7,8-dihydro-1,6-naphth...)
Affinity DataEC50:  290nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed