BDBM50337950 5-((3-fluorophenyl)ethynyl)isoindoline-1,3-dione::CHEMBL1684234

SMILES Fc1cccc(c1)C#Cc1ccc2C(=O)NC(=O)c2c1

InChI Key InChIKey=HPCFOCOTTGLLSI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337950   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337950(5-((3-fluorophenyl)ethynyl)isoindoline-1,3-dione |...)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed