BDBM50337952 5-((4-fluorophenyl)ethynyl)isoindoline-1,3-dione::CHEMBL1684236

SMILES Fc1ccc(cc1)C#Cc1ccc2C(=O)NC(=O)c2c1

InChI Key InChIKey=VLJOFHKOHGIVRZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337952   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337952(5-((4-fluorophenyl)ethynyl)isoindoline-1,3-dione |...)
Affinity DataEC50:  160nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed