BDBM50337960 6-(cyclopropylmethyl)-2-((3-fluorophenyl)ethynyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one::CHEMBL1684231

SMILES Fc1cccc(c1)C#Cc1ccc2C(=O)N(CC3CC3)CCc2n1

InChI Key InChIKey=RHLXQTMEYJUCHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337960   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337960(6-(cyclopropylmethyl)-2-((3-fluorophenyl)ethynyl)-...)
Affinity DataIC50: 660nMAssay Description:Antagonist activity against mGlu5 receptor assessed as inhibition of calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed