BDBM50337972 6-((2-fluorophenyl)ethynyl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL1684112

SMILES Fc1ccccc1C#Cc1ccc2C(=O)NCCc2c1

InChI Key InChIKey=DNVTWDKKJYJBDU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337972   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337972(6-((2-fluorophenyl)ethynyl)-3,4-dihydroisoquinolin...)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed