BDBM50338350 CHEMBL1682902::rac-6-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]-2,3-dihydro-1H-benzo[f]isoindol-1-one

SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc2cc3C(=O)NCc3cc2c1

InChI Key InChIKey=RTMHSNZDMYWGTC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338350   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338350(rac-6-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 36nMAssay Description:Inhibition of 17,20 lyase activity in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338350(rac-6-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 42nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338350(rac-6-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed