BDBM50338588 CHEMBL1683962::N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((4-(morpholinomethyl)phenyl)ethynyl)pyrimidin-4-amine

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=MHAZSVGHNFNZJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338588   

TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338588(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-...)
Affinity DataIC50: 240nMAssay Description:Inhibition of EGFR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338588(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-...)
Affinity DataIC50: 440nMAssay Description:Inhibition of HER2 by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed