BDBM50338599 CHEMBL1683973::N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-(5-(pyrrolidin-1-yl)pent-1-ynyl)pyrimidin-4-amine

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#CCCCN1CCCC1

InChI Key InChIKey=XRGMUYHNNJZTJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338599   

TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338599(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338599(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-...)
Affinity DataIC50: 95nMAssay Description:Inhibition of HER2 by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed