BDBM50338613 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidine-5-carbaldehyde O-3-morpholinopropyl oxime::CHEMBL1683959

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1\C=N\OCCCN1CCOCC1

InChI Key InChIKey=PUPXFZQHXRUOTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338613   

TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338613(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-me...)
Affinity DataIC50: 65nMAssay Description:Inhibition of EGFR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50338613(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-me...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HER2 by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed